Publications
* (co-) corresponding author
† (co-) first author
| [55] | J. T. Grün, C. Hennecker, D.-P. Klötzner, R. W. Harkness, I. Bessi, A. Heckel, A. K. Mittermaier*, H. Schwalbe* | |
| J. Am. Chem. Soc. 2020, 142, 264-273 DOI: 10.1021/jacs.9b10367 | ||
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Conformational Dynamics of Strand Register Shifts in DNA G-Quadruplexes |
| [54] | M. Scheurer*, P. Reinholdt, E. R. Kjellgren, J. M. H. Olsen, A. Dreuw, J. Kongsted* | |
| J. Chem. Theory Comput. 2019, 15, 6154-6163, DOI: 10.1021/acs.jctc.9b00758 | ||
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CPPE: An Open-Source C++ and Python Library for Polarizable Embedding |
| [53] | M Reese, C. George, C. Yang, S. Jawla, J. T. Grün, H. Schwalbe, C. Redfield, R. J. Temkin, R. G. Griffin* | |
| J. Magn. Reson. 2019, 307, 106573, DOI: 10.1016/j.jmr.2019.106573 | ||
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Modular, triple-resonance, transmission line DNP MAS probe for 500 MHz/330 GHz |
| [52] | R. Schnieders, S. Keyhani, H. Schwalbe*, B. Fürtig* | |
| Chem.Eur. J. 2019, 26, 102-113, DOI: 10.1002/chem.201903355 | ||
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More than Proton Detection—New Avenues for NMR Spectroscopy of RNAs |
| [51] | J. K. Bains, J. Blechar, V. de Jesus, N. Meiser, H. Zetzsche, B. Fürtig, H. Schwalbe, M. Hengesbach* | |
| Methods 2019, 153, 22-34, DOI: 10.1016/j.ymeth.2018.10.004 | ||
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Combined smFRET and NMR analysis of riboswitch structural dynamics |
| [50] | M. Reinfelds, V. Hermanns, T. Halbritter, J. Wachtveitl, M. Braun, T. Slanina, A. Heckel | |
| ChemPhotoChem. 2019 DOI: 10.1002/cptc.201900010 | ||
| [49] | C. Geiger, S. M. Korn, M. Häsler, O. Peetz, J. Martin, P. Kötter, N. Morgner, K.-D. Entian | |
| Appl. Environ. Microbiol. 2019, 85, e00534-19, DOI: 10.1128/AEM.00534-19 | ||
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LanI-Mediated Lantibiotic Immunity in Bacillus subtilis: Functional Analysis |
| [48] | P. Müller, P. Seyfried, A. Frühauf, A. Heckel | |
| Methods Enzymol. 2019 DOI: 10.1016/bs.mie.2019.04.019 | ||
| [47] | M. Asido, P. Eberhardt, C. N. Kriebel, M. Braun, C. Glaubitz, J. Wachtveitl | |
| Phys. Chem. Chem. Phys. 2019 DOI: 10.1039/C8CP07418F | ||
| [46] | M. Scheurer, M. F. Herbst, P. Reinholdt, J. M. H. Olsen, A. Dreuw | |
| J. Chem. Theory Comput. 2018 DOI: 10.1021/acs.jctc.8b00576 | ||
| [45] | K. Gatterdam, E. F. Joest, M. S. Dietz, M. Heilemann, R. Tampé | |
| Angew. Chem. Int. Ed. 2018 DOI: 10.1002/anie.201882061 | ||
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Frontispiece: Super‐Chelators for Advanced Protein Labeling in Living Cells |
| [44] | K. Falahati, H. Tamura, I. Burghardt*, M. Huix-Rotllant | |
| Nat. Commun. 2018 DOI: 10.1038/s41467-018-06615-1 |
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| Ultrafast Carbon Monoxide Photolysis and Heme Spin-Crossover in Myoglobin via Nonadiabatic Quantum Dynamics |
| [43] | I. Elamri†, M. Heumüller†, L.-M. Herzig, E. Stirnal, J. Wachtveitl, E. Schuman, H. Schwalbe* | |
| ChemBioChem 2018, 19, 1-8; DOI: 10.1002/cbic.201800408 |
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| A New Photocaged Pyromycin for an Efficient Labeling of Newly Translated Proteins in Living Neurons |
| [42] | F. Bourdeaux, C. A. Hammer, S. Vogt, F. Schweighöfer, G. Noll, J. Wachtveitl, M. Grininger* | |
| ACS Infect. Dis. 2018, 4, 1082-1092 |
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| Flavin Storage and Sequestration by Mycobacterium Tuberculosis Dodecin |
| [41] | P. Seyfried†, M. Heinz†, G. Pinter†, D.-P. Klötzner, Y. Becker, M. Bolte, H. R. A. Jonker, L. S. Stelzl, G. Hummer*, H. Schwalbe*, A. Heckel* | |
| Chem. Eur. J. DOI: 10.1002/chem.201804040 |
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| Optimal Destabilization of DNA Double Strands by Single-Nucleobase Caging |
| [40] | A. Lukin, J. Kramer, M. Hartmann, L. Weizel, V. Hernandez-Olmos, K. Falahati, I. Burghardt, N. Kalinchenkova, D. Bagnyukova, N. Zhurilo, J. Rautio, M. Forsberg, J. Ihalainen, S. Auriola, J. Leppänen, I. Konstantinov, D. Pogoryelov, E. Proschak, D. Dar'in, M. Krasavin* | |
| Bioorg. Chem. 2018, 80, 655 |
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| Discovery of Polar Spirocyclic Orally Bioavailable Urea Inhibitors of Soluble Epoxide Hydrolase |
| [39] | K. Gatterdam†, E. F. Joest†, V. Gatterdam, R. Tampé* | |
| Angew. Chem. Int. Ed. 2018, 57, 1-6 |
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| The Scaffold Design of Trivalent Chelator Heads Dictates Affinity and Stability for Labeling His-Tagged Proteins in Vitro and in Cells |
| [38] | S. Keyhani, T. Goldau, A. Blümler, A. Heckel*, H. Schwalbe* | |
| Angew. Chem. Int. Ed. 2018, DOI: 10.1002/anie.201807125 |
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| Chemo‐Enzymatic Synthesis of Position‐Specifically Modified RNA for Biophysical Studies including Light Control and NMR Spectroscopy |
| [37] | A. Klein, S. Hank, A. Raulf, E. F. Joest, F. Tissen, M. Heilemann, R. Wieneke*, R. Tampé* | |
| Chem. Sci. 2018, DOI: 10.1039/c8sc02910e | ||
| Live-Cell Labeling of Endogenous Proteins with Nanometer Precision by Transduced Nanobodies |
| [36] | V. Glembockyte, R. Wieneke, K. Gatterdam, Y. Gidi, R. Tampé*, G. Cosa* | |
| J. Am. Chem. Soc. 2018, DOI: 10.1021/jacs.8b04681 | ||
| Tris -N-Nitrilotriacetic Acid Fluorophore as a Self-Healing Dye for Single-Molecule Fluorescence Imaging |
| [35] | L. J. G. W. van Wilderen, H. Brunst, H. Gustmann, J. Wachtveitl, J. Broos, J. Bredenbeck* | |
| Phys. Chem. Chem. Phys. 2018, DOI: 10.1039/C8CP00846A | ||
| Cyano-Tryptophans as Dual Infrared and Fluorescence Spectroscopic Labels to Assess Structural Dynamics in Proteins |
| [34] | M. Reinfelds†, J. von Cosel†, K. Falahati, C. Hamerla, T. Slanina, I. Burghardt* and Alexander Heckel* | |
| Chem. Eur. J. 2018, DOI: 10.1002/chem.201802390 |
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| A New Photocage Derived from Fluorene |
| [33] | P. Mondal,* G. Granucci, D. Rastaedter, M. Persico* and I. Burghardt* | |
| Chem. Sci. 2018, DOI: 10.1039/C8SC00072G | ||
| Azobenzene as a Photoregulator Covalently Attached to RNA: a Quantum Mechanics/Molecular Mechanics- Surface Hopping Dynamics Study |
| [32] | K. Falahati, C. Hamerla, M. Huix-Rotllant* and I. Burghardt* | |
| Phys. Chem. Chem. Phys. 2018, DOI: 10.1039/C8CP00657A | ||
| Ultrafast Photochemistry of Free-Base Porphyrin: a Theoretical Investigation of B → Q Internal Conversion Mediated by Dark States |
| [31] | L. Dworak, S. Roth, M. P. Scheffer, A. S. Frangakis, J. Wachtveitl* | |
| Nanoscale 2018, 10, 2162-2169 | ||
| Thin CdSe Shell Boosts the Electron Transfer from CdTe Quantum Dots to Methylene Blue |
| [30] | K. Gatterdam, E. F. Joest, M. S. Dietz, M. Heilemann, R. Tampé | |
| Angew. Chem. Int. Ed. DOI: 10.1002/anie.201800827 | ||
| Super-Chelators for Advanced Protein Labeling in Living Cells |
| [29] | C. Helmling,† D. P. Klötzner,† F. Sochor, R. A. Mooney, A. Wacker, R. Landick, B. Fürtig, A. Heckel,* H. Schwalbe* | |
| Nat. Commun. 2018, 9, 944 | ||
| Life Times of Metastable States Guide Regulatory Signaling in Transcriptional Riboswitches |
| [28] | Y. Becker,† E. Unger,† M. A. H. Fichte, D. A. Gacek, A. Dreuw, J. Wachtveitl, P. J. Walla, A. Heckel* | |
| Chem. Sci. 2018, 9, 2797-2802 | ||
| A Red-Shifted Two-Photon-Only Caging Group for Three-Dimensional Photorelease |
| [27] | C. A. Hammer,† K. Falahati,† A. Jakob,† R. Klimek, I. Burghardt, A. Heckel,* J. Wachtveitl,* | |
| J. Phys. Chem. Lett. 2018, 9, 1448-1453 | ||
| Sensitized Two-Photon Activation of Coumarin Photocages |
| [26] | D. Kern-Michler,† C. Neumann,† N. Mielke, L. J. G. W. van Wilderen, M. Reinfelds, J. von Cosel, F. Santoro, A. Heckel, I. Burghardt, J. Bredenbeck* | |
| J. Am. Chem. Soc. 2018, 140, 926-931 | ||
| Controlling Photochemistry via Isotopomers and IR Pre-excitation |
| [25] | T. Stark, T. Lieblein, M. Pohland, E. Kalden, P. Freund, R. Zangl, R. Grewal, M. Heilemann, G. P. Eckert, N. Morgner, M. W. Göbel* | |
| Biochemistry 2017, 56, 4840-4849 | ||
| Peptidomimetics That Inhibit and Partially Reverse the Aggregation of Aβ1−42 |
| [24] | L. Dworak, S. Roth, J. Wachtveitl* | |
| J. Phys. Chem. C 2017, 121, 2613-2619 | ||
| Charge Transfer-Induced State Filling in CdSe Quantum Dot-Alizarin Complexes |
| [23] | C. Thomas, R. Tampé | |
| Science 2017, 358, 1060-1064 | ||
| Structure of the TAPBPR–MHC I Complex Defines the Mechanism of Peptide Loading and Editing |
| [22] | J. Hu, S. Dziumbla, J. Lin, S. Bibli, S. Zukunft, J. de Mos, K. Awwad, T. Frömmel, A. Jungmann, K. Devraj, Z. Cheng, L. Wang, S. Fauser, C. G. Eberhart, A. Sodhi, B. D. Hammock, S. Liebner, O. J. Müller, C. Glaubitz, H. P. Hammes, R. Popp, I. Fleming* | |
| Nature 2017, 552, 248-252 | ||
| Inhibition of Soluble Epoxide Hydrolases Prevents Diabetic Retinopathy |
| [21] | R. Schnieders, C. Richter, S. Warhaut, V. de Jesus, S. Keyhani, E. Duchardt-Ferner, H. Keller, J. Wöhnert, L. T. Kuhn, A. L. Breeze, W. Bermel, H. Schwalbe,* B. Fürtig* | |
| J. Biomol. NMR 2017, 69, 31-44 | ||
| Evaluation of 15N-Detected H-N correlation experiments on increasingly large RNA |
| [20] | G. Pintér, H. Schwalbe* | |
| Angew. Chem. Int. Ed. 2017, 56, 8332-8334 | ||
| Unprecedented Carbon Signal Enhancement in Liquid-State NMR Spectroscopy |
| [19] | H. Steinert, F. Sochor, A. Wacker, J. Buck, C. Helmling, F. Hiller, S. Keyhani, J. Noeske, S. Grimm, M. M. Rudolph, H. Keller, R. A. Mooney, R. Landick, B. Suess, B. Fürtig,* J. Wöhnert,* H. Schwalbe* | |
| eLife 2017, 6, e21297 | ||
| Pausing Guides RNA Folding to Populate Traniently Stable RNA Structures for Riboswitch-Based Transcription Regulation |
| [18] | L.-M. Herzig,† I. Elamri,† H. Schwalbe,* J. Wachtveitl* | |
| Phys. Chem. Chem. Phys. 2017, 19, 14835-14844 | ||
| Light-Induced Antibiotic Release from a Coumarin-Caged Compound on the Ultrafast Timescale |
| [17] | J. von Cosel, J. Cerezo, D. Kern-Michler, C. Neumann, L. J. G. W van Wilderen, J. Bredenbeck, F. Santoro,* I. Burghardt* | |
| J. Chem. Phys. 2017, 147, 164116 | ||
| Vibrationally Resolved Electronic Spectra Including Vibrational Pre-Excitation: Theory and Application to VIPER Spectroscopy |
| [16] | L. J. G. W. van Wilderen, C. Neumann, A. Rodrigues-Correia, D. Kern-Michler, N. Mielke, M. Reinfelds, A. Heckel, J. Bredenbeck* | |
| Phys. Chem. Chem. Phys. 2017, 19, 6487–6496 | ||
| Picosecond Activation of the DEACM Photocage Unravelled by VIS-pump-IR-probe Spectroscopy |
| [15] | D. P. Klötzner,† K. Klehs,† M. Heilemann,* A. Heckel* | |
| Chem. Commun. 2017, 53, 9874-9877 | ||
| A New Photoactivatable Near-Infrared-Emitting QCy7 Fluorophore for Single-Molecule Super-Resolution Microscopy |
| [14] | P. Seyfried, L. Eiden, N. Grebenovsky, G. Mayer,* A. Heckel* | |
| Angew. Chem. Int. Ed. 2017, 56, 359-363 | ||
| Photo-Tethers for the (Multi-)Cyclic, Conformational Caging of Long Oligonucleotides |
| [13] | F. Schweighöfer, L. Dworak, C. A. Hammer, H. Gustmann, M. Zastrow, K. Rück-Braun, J. Wachtveitl* | |
| Sci. Rep. 2016, 6, 28638 | ||
| Highly Efficient Modulation of FRET in an Orthogonally Arranged BODIPY–DTE Dyad |
| [12] | C. Slavov, C. Boumrifak, C. A. Hammer, P. Trojanowski, X. Chen, W. J. Lees, J. Wachtveitl, M. Braun* | |
| Phys. Chem. Chem. Phys. 2016, 18, 10289-10296 | ||
| The Ultrafast Reactions in the Photochromic Cycle of Water-Soluble Fulgimide Photoswitches |
| [11] | M. Braner, A. Kollmannsperger, R. Wieneke, R. Tampé* | |
| Chem. Sci. 2016, 7, 2646-2652 | ||
| ’Traceless’ Tracing of Proteins – High-Affinity Trans-Splicing Directed by a Minimal Interaction Pair |
| [10] | A. Kollmannsperger, A. Sharei, A. Raulf, M. Heilemann, R. Langer, K. F. Jensen, R. Wieneke,* R. Tampé* | |
| Nat. Commun. 2016, 7, 10372 | ||
| Live-Cell Protein Labelling with Nanometre Precision by Cell Squeezing |
| [9] | B. Fürtig,* R. Schnieders, C. Richter, H. Zetzsche, S. Keyhani, C. Helmling, H. Kovacs, H. Schwalbe* | |
| J. Biomol. NMR 2016, 64, 207-221 | ||
| Direct 13C-Detected NMR Experiments for Mapping and Characterization of Hydrogen Bonds in RNA |
| [8] | M. A. H. Fichte, X. M. M. Weyel, S. Junek, F. Schäfer, C. Herbivo, M. Goeldner, A. Specht, J. Wachtveitl, A. Heckel* | |
| Angew. Chem. Int. Ed. 2016, 55, 8948-8952 | ||
| Three-Dimensional Control of DNA Hybridization by Orthogonal Two-Color Two-Photon Uncaging |
| [7] | A. V. Kuzmin,* C. Neumann, L. J. G. W. van Wilderen, B. Shainyan, J. Bredenbeck* | |
| Phys. Chem. Chem. Phys. 2016, 18, 8662-8672 | ||
| Exploring Photochemistry of p-Bromophenylsulfonyl, p-Tolylsulfonyl and Methylsulfonyl Azides by Ultrafast Time-Resolved UV-pump – IR-Probe Spectroscopy and Computations |
| [6] | J. Maciejko, M. Mehler, J. Kaur, T. Lieblein, N. Morgner, O. Ouari, P. Tordo, J. Becker-Baldus, C. Glaubitz* | |
| J. Am. Chem. Soc. 2015, 137, 9032-9043 | ||
| Visualizing Specific Cross-Protomer Interactions in the Homo-Oligomeric Membrane Protein Proteorhodopsin by Dynamic-Nuclear-Polarization-Enhanced Solid-State NMR |
| [5] | C. Özçoban, T. Halbritter, S. Steinwand, L. M. Herzig, J. Kohl-Landgraf, N. Askari, F. Groher, B. Fürtig, C. Richter, H. Schwalbe, B. Suess, J. Wachtveitl,* A. Heckel* | |
| Org. Lett. 2015, 17, 1517-1520 | ||
| Water-Soluble Py-BIPS Spiropyrans as Photoswitches for Biological Applications |
| [4] | G. Fleischmann, O. Fisette, C. Thomas, R. Wieneke, F. Tumulka, C. Schneeweiss, S. Springer, L. V. Schäfer, R. Tampé* | |
| J. Immunol. 2015, 195, 4503-4513 | ||
| Mechanistic Basis for Epitope Proofreading in the Peptide-Loading Complex |
| [3] | R. Wieneke, A. Raulf, A. Kollmannsperger, M. Heilemann,* R. Tampé* | |
| Angew. Chem. Int. Ed. 2015, 54, 10216-10219 | ||
| SLAP: Small Labeling Pair for Single-Molecule Super-Resolution Imaging |
| [2] | C. Helmling,† S. Keyhani,† F. Sochor, B. Fürtig, M. Hengesbach, H. Schwalbe | |
| J. Biomol. NMR 2015, 63, 67-76 | ||
| Rapid NMR Screening of RNA Secondary Structure and Binding |
| [1] | T. R. M. Barends, L. Foucar, A. Ardevol, K. Nass, A. Aquila, S. Botha, R. B. Doak, K. Falahati, E. Hartmann, M. Hilpert, M. Heinz, M. C. Hoffmann, J. Koefinger, J. E. Koglin, G. Kovacsova, M. Liang, D. Milathianaki, H. Lemke, J. Reinstein, C. M. Roome, R. L. Shoeman, G. J. Williams, I. Burghardt, G. Hummer, S. Boutet, I. Schlichting | |
| Science 2015, 350, 445-450 | ||
| Direct Observation of Ultrafast Collective Motions in CO Myoglobin upon Ligand Dissociation |